Start by entering a set of genes/proteins you are interested in - perhaps those involved in a known model, a particular biochemical pathway or PPI network. Then select a normal tissue, cancer cell line or PDX model from the drop down list.
The tool will compile a visual interaction network around your query using IntAct PPI data, retaining only those entries expresssed in the selected sample (>1 TPM). Nodes are connected by PPI data, edges weighted by common Reactome pathways. Node size is weighted by sample-specific expression levels.